This manual offers guidelines for medication-assisted treatment for people, particularly veterans, living with post-traumatic stress disorder and co-occurring opioid use disorders. It covers screening, concomitant treatment, pharmacotherapy, and multiple misused substances.

This manual offers general principles to assist in the planning, delivery, and evaluation of pharmacologic approaches to support the recovery of people living with co-occurring disorders. It covers engagement, screening, assessment, treatment planning, and continuity of care.