This Clinical Guide provides comprehensive, national guidance for optimal management of pregnant and parenting women with opioid use disorder and their infants. The Clinical Guide helps healthcare professionals and patients determine the most clinically appropriate action for a particular situation and informs individualized treatment decisions.

This guide reviews child welfare, substance use disorder services, and courts to support cross-system coordination within state, county, and tribal jurisdictions. It considers the framework, population, legislation, funding sources, and services for each system.

Using a case study approach, this manual presents resources to better understand and engage the community in responding to children whose caregivers are negatively impacted by mental illness, substance use, or trauma.

This document examines treatment issues for both adult survivors of child abuse or neglect and adults in treatment who may be abusing or neglecting their own children.