The Rx Pain Medications. Know the Options. Get the Facts. is a series of 13 fact sheets designed to increase awareness of the risks associated with prescription opioid use and misuse, as well as to educate patients who are prescribed opioids for pain about the risks and to provide resources on methods for alternative pain management. This particular fact sheet focuses on how clinicians can discuss the appropriate use of opioids, dosage, and the dangers of opioid use disorder and overdose.