This manual provides guidelines for the operation of opioid treatment programs. It covers patient assessment, treatment planning, and recovery care. The manual also offers guidance for medication-assisted treatment for methadone and buprenorphine, and overdose and relapse prevention.

This guide reviews child welfare, substance use disorder services, and courts to support cross-system coordination within state, county, and tribal jurisdictions. It considers the framework, population, legislation, funding sources, and services for each system.