The fourth supplemental resource to SAMHSA’s Clinical Guidance for Treating Pregnant and Parenting Women with Opioid Use Disorder and Their Infants publication. This document contains information for pregnant people with a substance use disorder and preparing to deliver.

This Advisory is based on TIP 51, Substance Abuse Treatment: Addressing the Specific Needs of Women. It offers guidance to providers and administrators about the particular needs of women during substance use disorder (SUD) treatment.

This Clinical Guide provides comprehensive, national guidance for optimal management of pregnant and parenting women with opioid use disorder and their infants. The Clinical Guide helps healthcare professionals and patients determine the most clinically appropriate action for a particular situation and informs individualized treatment decisions.

This guide assists providers in offering treatment to women living with substance use disorders. It reviews gender-specific research and best practices, such as common patterns of initial use and specific treatment issues and strategies.

This quick guide helps clinicians address the specific needs of women living with substance use disorders. It reviews gender-specific research and best practices—such as common patterns of misuse—and specific screening and treatment strategies.